The 10 Best Ergonomic Gaming Mouse In 2021

Ergonomic Gaming Mouse

Although the mouse is an essential input device, it has arguably undergone the least design changes. A vital piece of hardware for most desktops and even laptops, mice are probably the most common hardware of choice for gaming setups as well. But traditional mice have a common design drawback.

Use a regular mouse for a long period and you are sure to feel a noticeable pain to your wrist and your upper arm. This is the design flaw to traditional mice – you need to bend your arm and your wrist to use them. And this is also where you should learn about ergonomic mice.

The first feature you will notice with an ergonomic mouse is the redesigned shape and contours. Some ergonomic gaming mice offer additional switches and functions to increase utility and input options. Others offer a vertical body shape where you don’t need to twist your arm and instead keep it naturally on its side for use.

If you are new to the concept of ergonomic mice or if you know what they are but unsure how they can help you with your gaming setup, read on!

Why Should You Use an Ergonomic Gaming Mouse?

Alongside your gaming keyboard, your setup should have an ergonomic gaming mouse. Why?

Firstly, ergonomic gaming mice are designed for comfort and to reduce usage stress. These mice will substantially negate the common wrist pain associated with prolonged use of regular mice.

You already know that traditional mice force you to twist your arm slightly. Also, these mice do not offer any added support to help you relax your wrist. An ergonomic mouse will be either be designed to help you use it without twisting your arm or it will provide the necessary support to reduce usage stress, or both.

Secondly, just like traditional gaming mice, ergonomic mice come with custom sensors designed for more accuracy and responsiveness. They also have a greater number of programmable buttons compared to conventional mice for more gaming utility.

Most ergonomic gaming mice also come with the necessary high DPI range for customizable performance based on your gameplay requirements. For instance, first-person shooter games like the upcoming Call of Duty Black Ops Cold War will require precision-driven lighter mice, preferably with add-on programmable buttons.

There are other factors too which you need to consider as well to accurately choose the best ergonomic gaming mouse for your gaming setup, viz. –


Grip is related to the mouse size. Make sure to check out whether the size of the mouse matches that of your hand. Too small or large a mouse will substantially reduce your productivity.

Wired or Wireless

Wired mice are cheaper and do not require batteries that make wireless mice heavier. Being heavy, wireless mice are often not the first choice when it comes to high-octane gaming. But they do offer more freedom of usage.

Vertical Design

Vertical mouse for gaming is purposely designed to allow you to rest your arm in a natural posture. This promotes both comfort and accuracy, especially while gaming for long hours.

You should consider opting for an ergonomic gaming mouse when –

  • You are troubled with wrist or arm pain that keeps you from long gaming hours. Or, if you have a tennis elbow or similar issues.
  • You want to upgrade to a gaming mouse better accessorized for personalization. Ergonomic gaming mice generally offer an array of programmable buttons and macro functions for customized usage.
  • You want to complement your gaming setup with a new-gen mouse.

Are Ergonomic Mice Good for Gaming?

Getting a well-designed ergonomic mouse can make a significant difference in your gameplay. It can give you the competitive edge along with comfort of use. Ordinary mice do not offer the same ergonomics or performance.

Ergonomic gaming mice are the future of mouse design and technology available for you today. Move forward from a 2 or 3 button basic mouse to a multi-button ergonomic gaming mouse.

Designed to be more utilitarian, these buttons can help you enjoy much more gaming functions, e.g. – Switch to grenades/flashbangs with a custom programmed mouse button, use combo moves without keyboard keys, etc.

So, get a suitable gaming mouse based on your gaming preferences and budget.

For you to help in that regard, We have come up with our top 10 best ergonomic gaming mice in 2021 and reviewed them for you!

More Ergonomic Related Product Reviews

Top 10 Best Ergonomic Gaming Mouse

1. Corsair Glaive

The Corsair Glaive Pro Gaming Mouse is a blend of gamer-friendly design ergonomics and high performance.

It has dynamic RGB backlighting across 3 lighting zones that can be customized with various colors and effects. The mouse offers 7 programmable buttons and 3 interchangeable thumb grips tailored for a personalized gaming experience.

The matte plastic on the top and 3 different side panels or thumb grips helps to customize the grip to suit almost every gamer. The mouse uses high performance Omron switches that are known for their long-lasting durability.

The Corsair Glaive Pro has a 5-level DPI indicator stretching up to 18000 for precise and sensitive tracking. It has an excellent sensor that works on almost all surfaces.

The ergonomic Corsair Glaive Pro gaming mouse is easy to use, requires no extra software or drivers to install and offers an optimum speed scroll wheel with dynamic RGB lighting.

Priced at around $70, this is one of the best native mice with gaming ergonomics.

Tech Specifications

Weight: 250 grams | Dimensions: 4.88 x 2.7 x 1.79 inches | DPI Levels: Up to 18,000 | No. of Buttons: 7 buttons with scroll wheel | Color: Black, Aluminum | Interface: USB 2.0, USB 3.0 | Compatibility: Windows, Mac


  • Contoured shape that fits all
  • Interchangeable thumb rests
  • Accurate sensor
  • 7 programmable buttons


  • Cable is stiff and heavy
  • Expensive


PICTEK Gaming Mouse Wired

This PICTEK mouse provides a wide DPI range from 1200 to 7200. DPI can be adjusted with the 2 buttons placed just under the middle button.

The high precision sensor makes gaming a breeze. It also offers customizable polling rates ranging from 125Hz to 1000Hz to decrease perceptible input lag.

This mouse comes with 7 programmable buttons including 2 additional keys on the side. The comfortable ergonomics promotes a confident grip along. The larger body helps decrease wrist fatigue.

All in all, the PICTEK wired gaming mouse bridges the gap between high-end performance and affordability. The above features make the cheapest ergonomic gaming mouse available today, priced at around $20.

Tech Specifications

Weight: 136 grams | Dimensions: 5.12 x 3.43 x 1.93 inches | DPI Levels: 1200, 2400, 3500, 5500, 7200 | No. of Buttons: 7 buttons with scroll wheel | Color: Black, RGB lighting | Interface: USB 2.0, USB 3.0 | Compatibility: Mac, Windows, PlayStation Vita


  • Budget buy
  • Comfortable grip
  • Wide range of DPI levels


  • Below par build quality
  • Compatibility issues

3. TRELC Ergonomic Mouse with 5D Rocker

The 5D rocker is an ergonomically designed vertical mouse that helps in reducing wrist pain and stress while offering optimum gaming performance.

The mouse has 2 RGB belts on either side with 5 lighting effects. It sports 11 programmable buttons along with a 5-direction rocker/joystick.

This is the first vertical ergonomic gaming mouse on this list. Notice the right-hand usage setup and grip patterns. Using this mouse, you can rest your wrist and avoid stress build up from long-term usage.

The left and right buttons are placed intuitively for the forefinger and middle finger accessibility. You will surely enjoy using the short joystick up top for WASD/directional and press/enter functions.

Besides, the page up and page down buttons on the bottom left is just as utilitarian as well.

DPI levels are adjustable to up to 10000 via the dedicated button placed with the primary button setup. DPI level is displayed via the easily visible quad-light cluster.

For under $30, this is the best ergonomic mouse available at this price range. It is perfectly suited for long gaming hours, offering utilitarian gaming along with sufficient performance.

Tech Specifications

Weight: 165 grams | Dimensions: 11 x 72 x 76.5 inches | DPI Levels: 1500, 2500, 4000, 7000, 10000 | No. of Buttons: 8 buttons including scroll wheel button plus Joystick | Color: Black, RGB lighting | Interface: USB 2.0, USB 3.0 | Compatibility: Windows


  • Ergonomic design
  • Programmable and customizable buttons
  • 20G acceleration
  • Varied DPI settings
  • Competitive gaming performance


  • Too small
  • Below-par build quality
  • Complicated add-on software

4. Razer Basilisk

Razer Basilisk Ultimate HyperSpeed Wireless Gaming Mouse

Razer has made a new addition to its gaming hardware collection, and this the ultimate best ergonomic gaming mouse you can add to your setup.

The Razer wireless Basilisk Ultimate sports textured rubber grips on both sides for ergonomic comfort and a premium sturdy feel.

You get 11 fully customizable buttons that can be remapped to individual commands. The hyper-efficient sensor provides a wide range of DPI levels from 800 to 20,000, one of the highest levels of DPI you can get.

The Basilisk gaming mouse uses a 4Ghz channel to ensure zero interference from any other connected device, a common issue among multi-hardware gaming setups.

Additionally, the Chroma lighting engine provides standard pre-sets of scrolling or breathing lights of the 7 rainbow colors and, an audio visualizer.

If you are willing to spare any amount of money for the ultimate best gaming hardware, the Razer Basilisk Ultimate is a must-have. It is the cutting-edge of gaming mice tech, but at around $150, this is definitely for professionals or the most passionate gamers.

Tech Specifications

Weight: 107 grams | Dimensions: 2.96 x 5.11 x 1.67 inches | DPI Levels: 800-20000 | No. of Buttons: 11 buttons with scroll wheel | Color: Black, Rainbow lighting | Interface: Micro USB | Compatibility: Windows


  • Extreme gaming performance
  • 20000 DPI sensor
  • Latency-free wireless connection
  • Wheel-tilt inputs


  • Expensive

5. UtechSmart Venus Gaming Mouse

UtechSmart Venus Gaming Mouse

The UtechSmart Venus wireless gaming mouse is equipped with a 1000-mAh battery that runs around 70 hours, a PixArt optical sensor, and boasts an extensive DPI range from 200 to 16400. This gaming mouse offers one of the most consistent CPIs and excellent sensor performance.

The ergonomic design of the mouse is suited towards right-handers with a rubber-coated surface for a firm grip. It also features 18 programmable and customizable buttons on its body and 16 million adjustable LED colors. You can personalize the 12-button array for a large range of functions for optimal utility.

The smooth and durable TEFLON design ensures a confident grip. The mouse contoured body provides superior control and basic ergonomics to reduce usage fatigue.

Other features like adjustable weight add-ons and the programming software bundled in make this UtechSmart Venus one of the top gaming mice around.

Priced at under $35, this is a must-buy if you are looking for extreme customizations for a competitive edge while gaming.

Tech Specifications

Weight: 220 grams | Dimensions: 4.6 x 3 x 1.5 inches | DPI Levels: Up to 16400 | No. of Buttons: 18 buttons with scroll wheel | Color: Black, RGB lighting | Interface: USB 2.0, USB 3.0 | Compatibility: Windows and Mac


  • Comfortable and well-built
  • High precision DPI sensor
  • Multiple programming buttons


  • Too large
  • Rigid and stiff cables
  • Difficult-to-use button cluster

6. Redragon SNIPER M801

Redragon SNIPER M801

The Redragon Sniper M801 is packed with a max 12400 DPI and a 30G Avago sensor. This wired mouse comes with gaming ergonomics and sports 9 programmable buttons, a Rapid-Fire button, 2 side buttons, and 5 different Memory Profiles bundled with Macro Recording.

The LED backlighting offers 8 different lighting effects, and this makes almost 50% of the mouse’s design.

For additional gaming features, the M801 offers 8-piece weight tuning, an anti-skid scroll wheel, and its bottom is equipped with durable and smooth TEFLON feet pads for the ultimate gaming control.

The package also includes 6 feet long 3mm high-speed braided cable with an anti-corrosive gold-plated USB connector.

The Redragon Sniper boasts a comfortable ergonomic design with extra rests on both sides to reduce usage fatigue. As for the side buttons, they are click-sensitive and use Omron keys, another praiseworthy feature.

However, you may take some time to adjust your fingers in controlling the buttons.

Tech Specifications

Weight: 158 grams | Dimensions: 4.8 x 1.6 x 3.2 inches | DPI Levels: 500, 1000, 2000, 4000, 6200, 12400 | No. of Buttons: 9 buttons with scroll wheel | Color: Black, RGB lighting | Interface: USB | Compatibility: Windows, Mac, Linux


  • Excellent price-to-performance
  • Precision laser sensor


  • Small switches

7. Jelly Comb

Jelly Comb Advanced Vertical Wireless Bluetooth Mouse

Another competitor for the best wireless ergonomic gaming mouse tag, this Jelly Comb vertical mouse is designed on the same handshake contours. But what sets this mouse apart from the rest is sheer value-for-money.

Jelly Comb keeps this mouse simple while ticking the right boxes with a great design, textured outer body, and simplicity of usage.

The rubbery plastic body comes with well-complemented grooves and the extended base offers sufficient wrist support.

The mouse comes with 5 buttons – 2 primary buttons, a scroll wheel, and a DPI switching button on side other than 2 forward and backward buttons on the thumb side.

Available DPI levels include 1000, 1600, and maxes out at 2400. However, this mouse has a trick up its sleeve.

Unlike most other ergonomic mice, this Jelly Comb Vertical Mouse offers dual connectivity options across Bluetooth and 2.4G.

So, it can connect with multiple other devices beyond PCs and laptops as well. You can use this mouse to run PUBG on your Android tablet as well.

This is perhaps the best ergonomic gaming mouse you can buy if you have not used such a mouse yet.

It is easy to operate for first-time users and considering its price tag of well under $30, this should be your first choice if you are on a budget.

Tech Specifications

Weight: 167 grams | Dimensions: 5.32 x 2.83 x 2.68 inches | DPI Levels: 1000, 1600, 2400 | No. of Buttons: 5 buttons with scroll wheel | Color: Black | Interface: 2.4G, Bluetooth 4.0 | Compatibility: Windows, Android, Mac OS, Linux


  • Budget buy
  • Simple usage
  • Multi-device compatibility
  • Nano USB receiver bundled in


  • Size not compatible for most users
  • Below par performance

8. Razer DeathAdder Essential

Razer DeathAdder Essential Gaming Mouse

The Razer DeathAdder Essential gaming mouse is rated one of the best gaming mice around with its comfortable ergonomic design, anti-slip grips and Razer’s gaming pedigree.

This is a medium-large size mouse that is more suitable for gamers with large palms. Moving on to the optical sensors, PixArt does the tracking with 30G acceleration and 5.6 m/s tracking speed.

The 5 mechanical programmable buttons offer a nice click-feel to your fingers. Enjoy up to 6400 from Razer’s industry-leading sensor pack for consistent and precise response.

Use Razer’s signature Synapse software tech to remap and program the buttons. Programmable options include complex macro functions as well.

The scroll wheel is rubberized for accuracy. Enjoy optimal tactile feedback to accurately control the wheel for high-end gameplay.

So, if you want an ergonomic gaming mouse with classic looks and enough features to elevate your gaming experience to the next level, you can buy the Razer DeathAdder Essential gaming mouse for under $30.

Tech Specifications

Weight: 123 grams | Dimensions: 5.01 x 2.86 x 1.69 inches | DPI Levels: 450, 900, 1800, 3500, 6400 | No. of Buttons: 5 buttons with scroll wheel | Color: Black, Green lighting | Interface: USB 3.0 | Compatibility: Windows


  • Value for money
  • Excellent PixArt sensor


  • Too large
  • Mandatory software log in

9. Evoluent VMCR VerticalMouse C Series

Evoluent VMCR VerticalMouse C Series

Evoluent was one of the first brands to introduce ergonomic mice in the market and this recent update is well worth a mention in this list.

This is a handshake-contoured mouse for ergonomic comfort of usage and popularly rated as an example of what an ergonomic mouse should be.

The Evoluent Vertical C series wired mouse stands out from the competition with its chrome finish on the thumb-side along with a thumb groove. On the button side, you get two primary buttons and a scroll wheel as well as a 3rd programmable button at the bottom.

The dedicated DPI switch is placed right before the scroll. The thumb groove itself is a cluster of 2 programmable buttons. Evoluent offers specific right-handed and left-handed models.

What makes this arguably the best vertical mouse for gaming is simply the sheer amount of utility and comfort you can get from this device. It is quite lightweight and competitively responsive at its highest available DPI.

With the Mouse Manager software added on, you can personalize your vertical mouse for different button functions and combinations, even specific to certain programs. Although it will take some getting used to, once you go vertical, you will surely never turn back to traditional.

The Evoluent C Series Wired mouse is priced at under $90 and is advertised for its comfort of use as well as utility. Get this mouse for your gaming setup if you are into marathon gaming sessions.

Tech Specifications

Weight: 140 grams | Dimensions: 3.55 x 3.15 x 4.69 inches | DPI Levels: 1600 | No. of Buttons: 5 buttons with scroll wheel | Color: Winter Blue | Interface: USB | Compatibility: Windows, Mac


  • Comfortable design elements
  • Simple to use and customize
  • Multiple programmable buttons


  • Below-par performance specs
  • Past generation product

10. Logitech MX

Logitech MX Vertical Wireless Mouse

Rated as the best wireless ergonomic gaming mouse available by many, the Logitech MX Vertical Mouse is designed with the natural handshake contours. It is popular as a user-friendly mouse targeted towards workstations, but it is just utilitarian as a gaming mouse.

This Logitech vertical mouse offers among the best performance and utility with its 4000 DPI sensor. Contrary to popular belief, you do not need a high DPI mouse for the best gaming experience. Instead, you need a mouse with an accurate sensor, just what this mouse offers.

You get the basic 3-button cluster on the left, a DPI level switching button up top other than 2 customizable buttons on the other side. The mouse provides a satisfactorily comfortable grip, further helped by the rubbered and textured outer body. This is also among the lightest wireless ergonomic mice you will come across.

Considering the cross-computer computability of up to 3 devices, this can be your first choice for single or multi-screen gaming. Although the price tag is around $90, this Logitech MX can be a great buy if it fits your requirements.

Tech Specifications

Weight: 227 grams | Dimensions: 5 x 4 x 4 inches | DPI Levels: Up to 4000 | No. of Buttons: 7 buttons with scroll wheel | Color: Winter Blue | Interface: USB | Compatibility: Windows


  • Superior ergonomics
  • Excellent sensor
  • Long lasting battery


  • Lack of programmable buttons
  • Expensive


What Mouse Do Pro Gamers Use?

Professional gamers use lighter mice with 3 to 4 programmed buttons. Many pro gamers use the SteelSeries Sensei Ten and the Razer DeathAdder gaming mice. Competitive gaming demands precise mouse movements so using high DPI settings around 4000 is common as well. Also, professionals prefer using lightweight mice in all circumstances.

Can You Use a Normal Mouse For Gaming?

Regular mice generally do not offer the same experience compared to gaming mice. For instance, the gaming mouse will provide improved software and hardware features that support both high CPI and DPI. A normal mouse is not ideal for gaming since it lacks these features and tends towards affordability or simple utility.

Is a Lighter Mouse Better For FPS?

Yes, a lighter mouse and adjustable DPI will allow you to control the mouse sensitivity for FPS. This lets you take aim or complete other point-and-click functions much faster than a generic mouse.

What DPI Do Most Gamers Use?

A higher DPI level is not always good for gaming. Irrespective of your play style, most ideally, a DPI range of 400 to 1600 is good for gaming. However, higher DPI does help increase tracking accuracy with minimal movements. Simply, high DPIs will let you cover more screen space with the same movement that at lower DPIs. But although this can help in better accuracy, the most suitable DPI range for a game depends more on your playing style and what settings you are used to.


Ergonomic mice will soon be the standard mouse design for the future. For gaming purposes, you will need your ergonomic mouse to offer varied DPI ranges and additional buttons as well. Ergonomics can refer to custom placed buttons or custom designed handshake-shaped vertical mouse or both. Reduce usage stress and enhance your gaming productivity with an ergonomic gaming mouse that best suits your requirements and your budget!